Chemokine (C-C Motif) Receptor 9 (CCR9) (C-Term), (AA 306-334) antibody

Details for Product No. ABIN657775
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Antigen
Synonyms AI464239, CCR10, CCR9, Ccbp2, Cmkbr9, D6, CCBP2, CMKBR9, hD6, CC-CKR-9, CDw199, GPR-9-6, GPR28, A130091K22Rik, Cmkbr10
Epitope
C-Term, AA 306-334
(11), (10), (7), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(50), (36), (14), (13), (13), (1)
Host
Rabbit
(33), (22), (15), (3)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(10), (7), (6), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(51), (16), (14), (10), (9), (6), (5), (4), (2), (2), (2), (1), (1)
Pubmed 4 references available
Quantity 400 μL
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Catalog No. ABIN657775
291.50 $
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Immunogen This CCR9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 306-334 AA from the C-terminal region of human CCR9.
Clone RB33876
Isotype Ig
Specificity This CCR9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-334 amino acids from the C-terminal region of human CCR9.
Predicted Reactivity Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name CCR9
Background The protein encoded by this gene is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are key regulators of the thymocytes migration and maturation in normal and inflammation conditions. The specific ligand of this receptor is CCL25. It has been found that this gene is differentially expressed by T lymphocytes of small intestine and colon, suggested a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract. This gene is mapped to the chemokine receptor gene cluster region. Two alternatively spliced transcript variants have been described.
Synonyms: C-C chemokine receptor type 9,CCR9,GPR28
Molecular Weight 42016 DA
Gene ID 10803
NCBI Accession NP_006632, NP_112477
UniProt P51686
Research Area Cell Signaling, Cell Structure, Protein Modifications
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.32 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment CCR9 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-Chemokine (C-C Motif) Receptor 9 (CCR9) (C-Term), (AA 306-334) antibody CCR9 Antibody (C-term) (ABIN657775) western blot analysis in MDA-MB435 cell line lysates (35 µg/lane). This demonstrates the CCR9 antibody detected the CCR9 protein (arrow).
Background publications Segat, Brandão, Guimarães et al.: "Polymorphisms in innate immunity genes and patients response to dendritic cell-based HIV immuno-treatment." in: Vaccine, Vol. 28, Issue 10, pp. 2201-6, 2010 (PubMed).

Dubois, Trynka, Franke et al.: "Multiple common variants for celiac disease influencing immune gene expression...." in: Nature genetics, Vol. 42, Issue 4, pp. 295-302, 2010 (PubMed).

Rajaraman, Brenner, Neta et al.: "Risk of meningioma and common variation in genes related to innate immunity." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 5, pp. 1356-61, 2010 (PubMed).

Han, Lan, Park et al.: "Polymorphisms in innate immunity genes and risk of childhood leukemia." in: Human immunology, Vol. 71, Issue 7, pp. 727-30, 2010 (PubMed).

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