Eukaryotic Translation Initiation Factor 4E Family Member 2 (EIF4E2) antibody

Details for Product No. ABIN659116
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Antigen
Synonyms Eif4el3, AI036339, AV129531, D0H0S6743E, 2700069E09Rik, 4EHP, IF4e, 4E-LP, EIF4EL3, EIF4E2, id:ibd1007, zgc:110542, zgc:158544, MGC115622
Reactivity
Human
(41), (4), (4), (1), (1), (1), (1)
Host
Mouse
(22), (19)
Clonality (Clone)
Monoclonal ()
Application
Western Blotting (WB)
(40), (10), (9), (8), (8), (3), (1), (1)
Pubmed 4 references available
Catalog no. ABIN659116
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This EIF4E2 monoclonal antibody is generated from mouse immunized with EIF4E2 recombinant protein.
Clone 225CT3-1-3
Isotype IgG1, kappa
Specificity This EIF4E2 monoclonal antibody is generated from mouse immunized with EIF4E2 recombinant protein.
Purification This antibody is purified through a protein G column, followed by dialysis against PBS.
Alternative Name EIF4E2
Background EIF4E2 recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.
Synonyms: Eukaryotic translation initiation factor 4E type 2,EIF4E2,EIF4EL3
Molecular Weight 28362 DA
Gene ID 9470
UniProt O60573, NP_004837.1
Research Area Translation Factors, Signaling, Protein Modifications, Chromatin, Cell Structure
Application Notes WB = 1:100-250
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Eukaryotic Translation Initiation Factor 4E Family Member 2 (EIF4E2) antibody EIF4E2/MB10227 antibody western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the EIF4E2/MB10227 antibody detected the EIF4E2/MB10227 protein (arrow).
Background publications Rosettani, Knapp, Vismara et al.: "Structures of the human eIF4E homologous protein, h4EHP, in its m7GTP-bound and unliganded forms." in: Journal of molecular biology, Vol. 368, Issue 3, pp. 691-705, 2007 (PubMed).

Zuberek, Kubacka, Jablonowska et al.: "Weak binding affinity of human 4EHP for mRNA cap analogs." in: RNA (New York, N.Y.), Vol. 13, Issue 5, pp. 691-7, 2007 (PubMed).

Venkatesan, Rual, Vazquez et al.: "An empirical framework for binary interactome mapping...." in: Nature methods, Vol. 6, Issue 1, pp. 83-90, 2008 (PubMed).

Watkins, Rukazenkov: "Response to 'Clinical outcomes in NSCLC patients with EGFR mutations: pooled analysis'
(Paz-Ares et al., J Cell Mol Med. 2010; 14: 51-69)." in: Journal of cellular and molecular medicine, Vol. 14, Issue 11, pp. 2693-4, 2010 (PubMed).

Hosts (22), (19)
Reactivities (41), (4), (4), (1), (1), (1), (1)
Applications (40), (10), (9), (8), (8), (3), (1), (1)
Epitopes (8), (3), (2)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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