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Eukaryotic Translation Initiation Factor 4E Family Member 2 (EIF4E2) antibody

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Synonyms EIF4E2, id:ibd1007, zgc:110542, zgc:158544, MGC115622, 4E-LP, 4EHP, EIF4EL3, IF4e, Eif4el3, 2700069E09Rik, AI036339, AV129531, D0H0S6743E
(104), (7), (7), (1), (1), (1), (1)
(61), (42), (1)
Clonality (Clone)
Monoclonal ()
(5), (5), (5), (5), (5), (5)
Western Blotting (WB)
(95), (54), (30), (11), (10), (5), (1)
Pubmed 4 references available
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Quantity 400 μL
Shipping to United States ( )
Availability Will be delivered in 10 to 11 Business Days
Immunogen This EIF4E2 monoclonal antibody is generated from mouse immunized with EIF4E2 recombinant protein.
Clone 225CT3-1-3
Isotype IgG1, kappa
Specificity This EIF4E2 monoclonal antibody is generated from mouse immunized with EIF4E2 recombinant protein.
Purification This antibody is purified through a protein G column, followed by dialysis against PBS.
Alternative Name EIF4E2 (EIF4E2 Antibody Abstract)
Background EIF4E2 recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.
Synonyms: Eukaryotic translation initiation factor 4E type 2,EIF4E2,EIF4EL3
Molecular Weight 28362 DA
Gene ID 9470
NCBI Accession NP_004837
UniProt O60573
Research Area Translation Factors, Signaling, Protein Modifications, Chromatin, Cell Structure
Application Notes WB = 1:100-250
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Eukaryotic Translation Initiation Factor 4E Family Member 2 (EIF4E2) antibody (ABIN659116) EIF4E2/MB10227 antibody western blot analysis in NCI-H460 cell line lysates (35ug/la...
Background publications Watkins, Rukazenkov: "Response to 'Clinical outcomes in NSCLC patients with EGFR mutations: pooled analysis'
(Paz-Ares et al., J Cell Mol Med. 2010; 14: 51-69)." in: Journal of cellular and molecular medicine, Vol. 14, Issue 11, pp. 2693-4, 2010 (PubMed).

Venkatesan, Rual, Vazquez et al.: "An empirical framework for binary interactome mapping...." in: Nature methods, Vol. 6, Issue 1, pp. 83-90, 2008 (PubMed).

Zuberek, Kubacka, Jablonowska et al.: "Weak binding affinity of human 4EHP for mRNA cap analogs." in: RNA (New York, N.Y.), Vol. 13, Issue 5, pp. 691-7, 2007 (PubMed).

Rosettani, Knapp, Vismara et al.: "Structures of the human eIF4E homologous protein, h4EHP, in its m7GTP-bound and unliganded forms." in: Journal of molecular biology, Vol. 368, Issue 3, pp. 691-705, 2007 (PubMed).

Catalog No. ABIN659116
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