Natriuretic Peptides B (NPPB) (AA 85-121) antibody (Cy5)

Details for Product No. ABIN678627, Supplier: Log in to see
Antigen
  • BNP1
  • NPPB
  • BNP
  • Bnf
  • AA408272
  • brain natriuretic peptide
  • natriuretic peptide B
  • natriuretic peptide type B
  • BNP
  • NPPB
  • Nppb
Alternatives
anti-Human Natriuretic Peptides B antibody for Enzyme Immunoassay
Epitope
AA 85-121
20
19
14
13
11
9
4
4
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine), Rat (Rattus)
180
23
18
2
1
1
1
Host
Rabbit
116
83
3
Clonality
Polyclonal
Conjugate
Cy5
10
9
9
5
5
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
95
88
38
37
16
16
5
4
2
2
2
2
2
1
1
1
1
1
Options
Supplier
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Immunogen KLH conjugated synthetic peptide derived from rat BNP
Isotype IgG
Purification Purified by Protein A.
Alternative Name BNP (NPPB Antibody Abstract)
Background

Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3 (By similarity).

Subcellular location: Secreted

Synonyms: BNP, Bnf, Natriuretic peptides B, Gamma-brain natriuretic peptide, Iso-ANP, Nppb

Gene ID 25105
UniProt P13205
Research Area Cardiovascular, Hypertrophy, Hormones
Pathways Hormone Activity
Application Notes IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 4°C
Expiry Date 12 months
Product cited in: Chavali, Tyagi, Mishra: "Differential expression of dicer, miRNAs, and inflammatory markers in diabetic Ins2+/- Akita hearts." in: Cell biochemistry and biophysics, Vol. 68, Issue 1, pp. 25-35, 2014 (PubMed).

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