Add to Basket
Order hotline:
 |
+1 404 474 4654 |
 |
+1 888 205 9894 (TF) |
JAB1 antibody
| Antigen | JAB1 |
| Clonality | Polyclonal |
| Host |
 Alternatives Rabbit |
| Reactivity |
Alternatives Human, Rat (Rattus), Mouse (Murine) |
| Application |
Alternatives Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Flow Cytometry (FACS), Immunofluorescence (IF)
|
| Catalog no. | ABIN685912 |
| Quantity | 100 µg (1mg/1ml) |
| Price | 255.00 $ Plus shipping costs $35.00 |
| Shipping to |
|
| Availability | Ships within 5 to 7 Business Days |
Additional Information
| Immunogen | Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human Jab1 C-terminus |
| Format | Lyophilized |
| Reconstitution | Reconstitute with 100ul sterille distilled water. After reconstitution, stock concentration=1ug/1ul, preservatives included (BSA=10ug/ul, Sodium azide=0.1%) |
| Isotype | IgG (Matching secondary antibodies) |
| Description | Synonym: 38 kDa Mov34 homolog, COP9 (constitutive photomorphogenic) homolog subunit 5, COP9 constitutive photomorphogenic homolog subunit 5, COP9 signalosome complex subunit 5, COP9 signalosome subunit 5, Cop9 subunit 5, COPS 5, COPS5, CSN 5, CSN5, JAB 1, Jun activation domain binding protein 1, Jun activation domain-binding protein, MGC3149, MOV 34, MOV34, SGN 5, SGN5, Signalosome subunit 5. |
| Molecular Weight | 37kDa |
| Comments |
The protein encoded by this gene is one of the eight subunits of COP9 signalosome a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. |
Application Details
| Application Notes | WB (1:100-500), ELISA (1:500-1000), IP (1:20-100), IHC-P (1:100-500), IHC-F (1:100-500), Flow-Cyt (1:20-100), IF (1:50-200) |
| Concentration | 1mg/1ml |
| Purification | affinity purified by Protein A |
| Buffer | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
| Storage | Ship at room temperature. Store at -20°C |
| Restrictions | For Research Use only |
Alternatives
Alternatives for antigen "JAB1", type "Antibodies"
| Hosts | Rabbit (21) |
| Reactivities | Human (21), Mouse (Murine) (20), Rat (Rattus) (20), Chicken (3), Pig (Porcine) (2), Cow (Bovine) (1), Dog (Canine) (1), Horse (Equine) (1), Rabbit (1), Zebrafish (Brachydanio rerio) (1) |
| Applications | Immunofluorescence (IF) (18), Flow Cytometry (FACS) (17), Western Blotting (WB) (4), ELISA (3), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (1), Immunohistochemistry (IHC) (1), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (1), Immunoprecipitation (IP) (1) |
| Conjugates | Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1) |
