» Antibodies » anti-JAB1 antibody (Cy5)

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JAB1 antibody (Cy5)

Antigen	JAB1
Clonality	Polyclonal
Host	Alternatives Rabbit Rabbit (21)
Reactivity	Alternatives Human, Rat (Rattus), Mouse (Murine) Human (21), Mouse (Murine) (20), Rat (Rattus) (20), Chicken (3), Pig (Porcine) (2), Cow (Bovine) (1), Dog (Canine) (1), Horse (Equine) (1), Rabbit (1), Zebrafish (Brachydanio rerio) (1)
Conjugate	Alternatives Cy5 Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Application	Alternatives Flow Cytometry (FACS), Immunofluorescence (IF) Immunofluorescence (IF) (18), Flow Cytometry (FACS) (17), Western Blotting (WB) (5), ELISA (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (2), Immunoprecipitation (IP) (2), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (IHC) (1)

Catalog no.	ABIN685916
Quantity	100 µg (1mg/1ml)
Price	330.00 $ Plus shipping costs $35.00
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Availability	Ships within 10 to 15 Business Days

Additional Information
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Immunogen	Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human Jab1 C-terminus
Format	Lyophilized
Reconstitution	Reconstitute with 100ul sterille distilled water. After reconstitution, stock concentration=1ug/1ul, preservatives included (BSA=10ug/ul, Sodium azide=0.1%)
Isotype	IgG
Description	Synonym: 38 kDa Mov34 homolog, COP9 (constitutive photomorphogenic) homolog subunit 5, COP9 constitutive photomorphogenic homolog subunit 5, COP9 signalosome complex subunit 5, COP9 signalosome subunit 5, Cop9 subunit 5, COPS 5, COPS5, CSN 5, CSN5, JAB 1, Jun activation domain binding protein 1, Jun activation domain-binding protein, MGC3149, MOV 34, MOV34, SGN 5, SGN5, Signalosome subunit 5.
Specificity	Excitation / Emission Wavelengths: 650nm/670nm
Molecular Weight	37kDa
Comments	The protein encoded by this gene is one of the eight subunits of COP9 signalosome a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors.

Application Details
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Application Notes	Flow-Cyt (1:50-200), IF (1:50-200)
Concentration	1mg/1ml
Purification	Antibodies are purified by protein A and peptide affinity chromatography.
Buffer	0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
Storage	Ship at room temperature. Store at -20°C
Restrictions	For Research Use only

Alternatives
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Alternatives for antigen "JAB1", type "Antibodies"

Hosts	Rabbit (21)
Reactivities	Human (21), Mouse (Murine) (20), Rat (Rattus) (20), Chicken (3), Pig (Porcine) (2), Cow (Bovine) (1), Dog (Canine) (1), Horse (Equine) (1), Rabbit (1), Zebrafish (Brachydanio rerio) (1)
Applications	Immunofluorescence (IF) (18), Flow Cytometry (FACS) (17), Western Blotting (WB) (5), ELISA (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (2), Immunoprecipitation (IP) (2), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (IHC) (1)
Conjugates	Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)