NCOR2 antibody (AA 2201-2525) (Cy5)

Catalog No. ABIN686306

The Rabbit Polyclonal anti-NCOR2 antibody is suitable to detect NCOR2 in samples from Human. It has been validated for IF (cc) and IF (p).

Quick Overview for NCOR2 antibody (AA 2201-2525) (Cy5) (ABIN686306)

Target: NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCOR2 antibody is conjugated to Cy5

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-NCOR2 Antibody (Cy5)

Binding Specificity: AA 2201-2525

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NCOR2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for NCOR2

Target: NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))

Alternative Name: Ncor2

Background:

Synonyms: Nuclear receptor corepressor 2, N-CoR2, Silencing mediator of retinoic acid and thyroid hormone receptor, SMRT, Thyroid- retinoic-acid-receptor-associated corepressor, T3 receptor-associating factor, TRAC, CTG repeat protein 26, SMAP270.

Background: NCoR2_Nuclear receptor corepressor 2_mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5 have different affinities for different nuclear receptors.

Gene ID: 9612

UniProt: Q9Y618

Pathways: Notch Signaling, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha