TFAP2A antibody (AA 351-437)

Catalog No. ABIN700945

This Rabbit Polyclonal antibody specifically detects TFAP2A in WB, ELISA, IHC (p), IF (p), IHC (fro) and IF (cc). It exhibits reactivity toward Human.

Quick Overview for TFAP2A antibody (AA 351-437) (ABIN700945)

Target: TFAP2A (Transcription Factor AP-2 alpha (Activating Enhancer Binding Protein 2 Alpha) (TFAP2A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFAP2A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc))

Product Details anti-TFAP2A Antibody

Binding Specificity: AA 351-437

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human AP2 alpha

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TFAP2A

Target: TFAP2A (Transcription Factor AP-2 alpha (Activating Enhancer Binding Protein 2 Alpha) (TFAP2A))

Alternative Name: AP2 alpha

Background:

Synonyms: Activating enhancer binding protein 2 alpha, Activating enhancer-binding protein 2-alpha, Activator protein 2, AP 2, AP 2 transcription factor, AP 2alpha, AP-2, AP-2 transcription factor, AP2, AP2 Transcription Factor, AP2-alpha, AP2A_HUMAN, AP2TF, BOFS, Clathrin Adaptor Protein Complex, FLJ51761, TFAP 2, TFAP 2A, TFAP2, TFAP2A, Transcription factor AP 2 alpha activating enhancer binding protein 2 alpha, Transcription factor AP 2 alpha, Transcription factor AP-2-alpha, Transcription factor AP2 alpha.

Background: The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.

Gene ID: 7020

Pathways: Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Response to Water Deprivation, Sensory Perception of Sound, Tube Formation, Embryonic Body Morphogenesis, Brown Fat Cell Differentiation, Lipid Metabolism