SERPING1 antibody (AA 401-500) (Cy7)

Catalog No. ABIN715487

The Rabbit Polyclonal anti-SERPING1 antibody is suitable to detect SERPING1 in samples from Human. It has been validated for WB, IF (cc) and IF (p).

Quick Overview for SERPING1 antibody (AA 401-500) (Cy7) (ABIN715487)

Target: SERPING1 (Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1 (SERPING1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERPING1 antibody is conjugated to Cy7

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-SERPING1 Antibody (Cy7)

Binding Specificity: AA 401-500

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Pig,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SERPING1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SERPING1

Target: SERPING1 (Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1 (SERPING1))

Background:

Synonyms: C1 esterase inhibitor, C1 INH, C1 inhibitor, C1-inhibiting factor, C1IN, C1Inh, C1NH, esterase inhibitor, HAE1, IC1_HUMAN, Plasma protease C1 inhibitor, Serine or cysteine proteinase inhibitor clade G member 1, Serpin G1, SERPING1.

Background: C1 Inactivator is a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform.

Gene ID: 710

Pathways: Complement System