SERPING1 antibody
Quick Overview for SERPING1 antibody (ABIN7259610)
Target
See all SERPING1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogen
- Recombinant fusion protein of human C1 Inactivator (NP_001027466.1).
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Isotype
- IgG
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Application Notes
- WB 1:1000-1:2000 IF 1:50-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- SERPING1 (Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1 (SERPING1))
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Alternative Name
- C1 Inactivator
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Background
- This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform.
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Molecular Weight
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Observed_MW: 60 kDa.110 kDa
Calculated_MW: 49 kDa/55 kDa
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Gene ID
- 710
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UniProt
- P05155
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Pathways
- Complement System
Target
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