KCNMA1 antibody (AA 1151-1236)

Catalog No. ABIN729178

This Rabbit Polyclonal antibody specifically detects KCNMA1 in IHC (p) and IHC (fro). It exhibits reactivity toward Rat.

Quick Overview for KCNMA1 antibody (AA 1151-1236) (ABIN729178)

Target: KCNMA1 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNMA1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-KCNMA1 Antibody

Binding Specificity: AA 1151-1236

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BK channel

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for KCNMA1

Target: KCNMA1 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1))

Alternative Name: BK channel

Background:

Synonyms: Maxi Potassium channel alpha, bA205K10.1, BK channel, BKCa channels, BKCA alpha, BKCA alpha subunit, BKTM, Calcium activated potassium channel subfamily M subunit alpha 1, Calcium activated potassium channel subunit alpha 1, DKFZp686K1437, Drosophila slowpoke like, hSlo, KVCAalpha, KCa1.1, KCNMA 1, KCNMA, KCNMA1, Large conductance calcium activated potassium channel subfamily M alpha member 1, Maxi K, Maxi K channel, MaxiK, Potassium large conductance calcium activated channel subfamily M alpha member 1, SAKCA, Slo 1, SLO alpha, SLO, Slo homolog, Slo1, Slowpoke homolog, Stretch activated Kca channel, KCMA1_HUMAN.

Background: MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

Gene ID: 3778

Pathways: Regulation of Hormone Metabolic Process, Sensory Perception of Sound