SLC27A2 antibody (AA 401-500) (Cy5.5)

Catalog No. ABIN751398

The Cy5.5-conjugated Rabbit Polyclonal anti-SLC27A2 antibody (ABIN751398) specifically detects SLC27A2 in WB, IF (cc) and IF (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SLC27A2 antibody (AA 401-500) (Cy5.5) (ABIN751398)

Target: SLC27A2 (Solute Carrier Family 27 (Fatty Acid Transporter), Member 2 (SLC27A2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC27A2 antibody is conjugated to Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-SLC27A2 Antibody (Cy5.5)

Binding Specificity: AA 401-500

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SLC27A2/ACSVL1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SLC27A2

Target: SLC27A2 (Solute Carrier Family 27 (Fatty Acid Transporter), Member 2 (SLC27A2))

Alternative Name: SLC27A2/ACSVL1

Background:

Synonyms: VLCS, FATP2, VLACS, ACSVL1, FACVL1, hFACVL1, HsT17226, Very long-chain acyl-CoA synthetase, Fatty acid transport protein 2, FATP-2, Fatty-acid-coenzyme A ligase, very long-chain 1, Long-chain-fatty-acid--CoA ligase, Solute carrier family 27 member 2, THCA-CoA ligase, Very long-chain-fatty-acid-CoA ligase, SLC27A2

Background: Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precurors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism. May be involved in translocation of long-chain fatty acids (LFCA) across membranes (By similarity).

Gene ID: 11001

UniProt: O14975

Pathways: Monocarboxylic Acid Catabolic Process, SARS-CoV-2 Protein Interactome