SLC27A2 antibody (AA 346-405)

Catalog No. ABIN1724864

Product Details anti-SLC27A2 Antibody

Target: SLC27A2 (Solute Carrier Family 27 (Fatty Acid Transporter), Member 2 (SLC27A2))

Binding Specificity: AA 346-405

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SLC27A2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Purpose: SLC27A2 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human SLC27A2 (AA: 346-405) expressed in E. Coli.

Clone: 6B3A9

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-SLC27A2 antibody (ABIN1724864)

Mishima, Miner, Morizane, Stahl, Sadovsky: "The expression and function of fatty acid transport protein-2 and -4 in the murine placenta." in: PLoS ONE, Vol. 6, Issue 10, pp. e25865, (2011) (PubMed).

Campa, Hüsing, Chang-Claude, Dostal, Boeing, Kröger, Tjønneland, Roswall, Overvad, Dahm, Rodríguez, Sala, Pérez, Larrañaga, Chirlaque, Ardanaz, Khaw, Wareham, Allen, Travis, Trichopoulou, Naska et al.: "Genetic variability of the fatty acid synthase pathway is not associated with prostate cancer risk in the European Prospective Investigation on Cancer (EPIC). ..." in: European journal of cancer (Oxford, England : 1990), Vol. 47, Issue 3, pp. 420-7, (2011) (PubMed).

Target Details for SLC27A2

Target: SLC27A2 (Solute Carrier Family 27 (Fatty Acid Transporter), Member 2 (SLC27A2))

Alternative Name: SLC27A2 (SLC27A2 Products)

Background:

Description: The protein encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes, but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Aliases: VLCS, FATP2, VLACS, ACSVL1, FACVL1, hFACVL1, HsT17226

Molecular Weight: 70.3kDa

Gene ID: 11001

HGNC: 11001

UniProt: O14975

Pathways: Monocarboxylic Acid Catabolic Process, SARS-CoV-2 Protein Interactome