Solute Carrier Family 27 (Fatty Acid Transporter), Member 2 (SLC27A2) (AA 346-405) antibody

Details for Product No. ABIN1724864
Antigen
Epitope
AA 346-405
15
4
2
1
1
1
1
1
Reactivity
Human
61
38
36
1
1
1
1
1
1
Host
Mouse
50
11
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
5
3
3
3
3
3
3
3
3
1
1
1
1
1
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
27
25
18
13
4
4
2
1
1
Options
Immunogen Purified recombinant fragment of human SLC27A2 (AA 346-405) expressed in E. Coli.
Clone 6B3A9
Isotype IgG1
Purification Purified
Antigen
Alternative Name SLC27A2 (SLC27A2 Antibody Abstract)
Background The protein encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes, but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. , ,
Molecular Weight 70.3 kDa
Gene ID 11001
HGNC 11001
Pathways Monocarboxylic Acid Catabolic Process, SARS-CoV-2 Protein Interactome
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Supplier Images
Image no. 1 for anti-Solute Carrier Family 27 (Fatty Acid Transporter), Member 2 (SLC27A2) (AA 346-405) antibody (ABIN1724864) Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using SLC...
Image no. 2 for anti-Solute Carrier Family 27 (Fatty Acid Transporter), Member 2 (SLC27A2) (AA 346-405) antibody (ABIN1724864) Immunohistochemical analysis of paraffin-embedded liver cancer tissues using SLC27A2 ...
Product cited in: Mishima, Miner, Morizane, Stahl, Sadovsky: "The expression and function of fatty acid transport protein-2 and -4 in the murine placenta." in: PLoS ONE, Vol. 6, Issue 10, pp. e25865, 2011 (PubMed).

Campa, Hüsing, Chang-Claude, Dostal, Boeing, Kröger, Tjønneland, Roswall, Overvad, Dahm, Rodríguez, Sala, Pérez, Larrañaga, Chirlaque, Ardanaz, Khaw, Wareham, Allen, Travis, Trichopoulou, Naska et al.: "Genetic variability of the fatty acid synthase pathway is not associated with prostate cancer risk in the European Prospective Investigation on Cancer (EPIC). ..." in: European journal of cancer (Oxford, England : 1990), Vol. 47, Issue 3, pp. 420-7, 2011 (PubMed).