TBL1XR1 antibody

Catalog No. ABIN781246

The Mouse Monoclonal anti-TBL1XR1 antibody (ABIN781246) specifically detects TBL1XR1 in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for TBL1XR1 antibody (ABIN781246)

Target: TBL1XR1 (Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TBL1XR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TBL1XR1 Antibody

Specificity: Nucleus

Purification: Protein G-Sepharose affinity purified.

Immunogen: Recombinant full length of Human TBLR1.

Application Details

Application Notes: Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 50µg/50µl

Buffer: 0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for TBL1XR1

Target: TBL1XR1 (Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1))

Alternative Name: TBL1XR1

Background: TBLR1 is an F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. It plays an essential role in transcription activation mediated by nuclear receptors and probably acts as an integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteosomal degradation of the N-Cor complex, thereby allowing cofactor exchange, and transcription activation.

Molecular Weight: 60kDa

Pathways: Regulation of Lipid Metabolism by PPARalpha