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SMARCA4 antibody (N-Term)
SMARCA4
Reactivity: Human, Mouse, Rat, Dog
IHC (p)
Host: Goat
Polyclonal
unconjugated
Product Details anti-SMARCA4 Antibody
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Target
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SMARCA4
(SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4))
Binding Specificity
All epitopes for SMARCA4 antibodies
AA 2-14, N-Term
Reactivity
All reactivities for SMARCA4 antibodies
Human, Mouse, Rat, Dog
Host
All hosts for SMARCA4 antibodies
Goat
Clonality
All clonalities for SMARCA4 antibodies
Polyclonal
Conjugate
All conjugates for SMARCA4 antibodies
This SMARCA4 antibody is un-conjugated
Application
All applications for SMARCA4 antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
This antibody reacts to Global Transcription Activator Snf2l4 (SMARCA4).
Cross-Reactivity (Details)
Species reactivity (expected):Canine, Mouse and Rat. Species reactivity (tested):Human.
Purification
Immunoaffinity Chromatography
Immunogen
Synthetic peptide STPDPPLGGTPRP-C from from the N-terminus of Human SMARCA4 / BRG1 (NP_001122321.1, NP_003063.2, NP_001122317.1, NP_001122318.1, NP_001122319.1, NP_001122320.1). Genename: SMARCA4 .Remarks: Antigen Modification: Amino Acids 2-14
Isotype
IgG
Top Product
Discover our top product SMARCA4 Primary Antibody
Alternatives
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anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4) (AA 1420-1470), (C-Term) antibody
SMARCA4
Reactivity: Human, Mouse, Rat
WB, ELISA, IF, IHC (p), CUT&RUN
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Tris saline buffer, pH 7.3 containing 0.5 % BSA as stabilizer and 0.02 % Sodium Azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Target Details for SMARCA4
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Target
SMARCA4
(SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4))
Alternative Name
SMARCA4 / BRG1 (SMARCA4 Products )
Synonyms
SMARCA4 antibody, BAF190 antibody, BAF190A antibody, BRG1 antibody, MRD16 antibody, RTPS2 antibody, SNF2 antibody, SNF2L4 antibody, SNF2LB antibody, SWI2 antibody, hSNF2b antibody, brg-1 antibody, Brg1 antibody, HP1-BP72 antibody, SNF2beta antibody, SW1/SNF antibody, b2b692Clo antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 antibody, SMARCA4 antibody, Smarca4 antibody
Background
Brg1 (Brahma-related gene 1) is an ATPase subunit of SWI2/SNF2-like chromatin-remodeling complexes that enable access of regulatory and effector proteins in transcription, DNA repair and DNA replication. Although Brg1-containing complexes are not essential for general cell survival, they participate in transcriptional regulation of several hundred genes including those involved in interferon and stress response, immune cells differentiation, neurogenesis, cell cycle etc. and is absolutely necessary for mouse embryogenesis. Brg1 is also involved in cell growth arrest, senescence and tumour supression.Synonyms: ATP-dependent helicase SMARCA4, BRG-1 protein, Brahma protein homolog 1, Mitotic growth and transcription activator, Probable global transcription activator SNF2L4, SNF2-beta, SNF2B, SNF2L4, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4
Gene ID
6597
NCBI Accession
NP_001122316
UniProt
P51532
Pathways
Intracellular Steroid Hormone Receptor Signaling Pathway , Regulation of Intracellular Steroid Hormone Receptor Signaling , Stem Cell Maintenance
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