SOX2 antibody (AA 76-80)
Quick Overview for SOX2 antibody (AA 76-80) (ABIN783321)
Target
See all SOX2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 76-80
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Sequence
- G-A-E-W-K
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Specificity
- This antibody detects endogenous level of total SOX2 protein.
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Cross-Reactivity (Details)
- Species reactivity (tested):Human, Mouse
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Purification
- Affinity-chromatography using epitope-specific peptide
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Immunogen
- Peptide sequence around aa.76~80 derived from SOX2
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.0 mg/mL
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Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- -20 °C
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Storage Comment
- Store (in aliquots) at -20 °C.
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- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
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Alternative Name
- SOX2
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Background
- Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.Synonyms: ANOP3, MCOPS3, SRY (sex determining region Y)-box 2, SRY-box 2, SRY-related HMG-box gene 2, Transcription factor SOX-2
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Molecular Weight
- 35 kDa
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Gene ID
- 6657
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NCBI Accession
- NP_003097
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UniProt
- P48431
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Pathways
- Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
Target
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