TCF12 antibody (N-Term)
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- Target See all TCF12 Antibodies
- TCF12 (Transcription Factor 12 (TCF12))
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Binding Specificity
- N-Term
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TCF12 antibody is un-conjugated
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificity
- This antibody detects TCF12 at N-term.
- Cross-Reactivity (Details)
- Species reactivity (tested):Human, mouse, rat
- Purification
- Affinity chromatography purified via peptide column
- Immunogen
- 19 amino acid peptide near the amino terminus of human TCF12
- Top Product
- Discover our top product TCF12 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- PBS containing 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- Target
- TCF12 (Transcription Factor 12 (TCF12))
- Alternative Name
- TCF12 (TCF12 Products)
- Background
- TCF12, also known as HTF4, is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. TCF12 is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. TCF12, in combination with E2A, is required to block thymocyte proliferation prior to pre-TCR expression and is critical for proper T cell differentiation. Recent reports have shown that TCF12 is also a critical factor required for the development of invariant natural killer T cells.Synonyms: DNA-binding protein HTF4, E-box-binding protein, HEB, HTF-4, HTF4, Transcription factor 12, Transcription factor HTF-4
- Gene ID
- 6938
- NCBI Accession
- NP_003196
- UniProt
- Q99081
- Pathways
- SARS-CoV-2 Protein Interactome
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