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Piwi-Like 3 (Drosophila) (PIWIL3) (N-Term) antibody

Details for Product No. ABIN783769, Supplier: Log in to see
Antigen
  • HIWI3
Epitope
N-Term
2
2
2
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
12
4
3
Host
Rabbit
10
2
Clonality
Polyclonal
Conjugate
Un-conjugated
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
8
7
6
1
1
Supplier
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Immunogen 18 amino acid peptide near the amino terminus of human PIWI-L3
Specificity This antibody detects PIWIL3 at N-term.
Cross-Reactivity (Details) Species reactivity (tested):Human, mouse, rat
Purification Affinity chromatography purified via peptide column
Alternative Name PIWIL3 (PIWIL3 Antibody Abstract)
Background PIWI-L3 is a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that are crucial for the biogenesis and function of small non-coding RNAs and play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. Recent studies have shown that overexpression of PIWI-L3 (as well as other PIWI-like proteins) are potential biomarkers for astrocytic glioma, meningioma, and other cancers.Synonyms: HIWI3, Piwi-like protein 3
Gene ID 440822
NCBI Accession NP_001008496
UniProt Q7Z3Z3
Research Area Chromatin and Nuclear Signaling, Reproduction
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Buffer PBS containing 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Piwi-Like 3 (Drosophila) (PIWIL3) (N-Term) antibody (ABIN783769) Western blot analysis of PIWI-L3 in 3T3 cell lysate with PIWI-L3 antibody at 1 μg/ml ...
Background publications Thomson, Lin: "The biogenesis and function of PIWI proteins and piRNAs: progress and prospect." in: Annual review of cell and developmental biology, Vol. 25, pp. 355-76, 2009 (PubMed).

Wang, Chen, Gao et al.: "[Preparation and distribution of polyclonal antibodies against human PIWIL3 protein in tumor tissues]." in: Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, Vol. 24, Issue 7, pp. 714-6, 2008 (PubMed).

Sasaki, Shiohama, Minoshima et al.: "Identification of eight members of the Argonaute family in the human genome small star, filled." in: Genomics, Vol. 82, Issue 3, pp. 323-30, 2003 (PubMed).