Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

CDC23 antibody (Center)

CDC23 Reactivity: Human, Mouse, Rat WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN783825
  • Target See all CDC23 Antibodies
    CDC23 (Cell Division Cycle 23 (CDC23))
    Binding Specificity
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivity
    • 50
    • 32
    • 19
    • 7
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    Human, Mouse, Rat
    Host
    • 48
    • 2
    Rabbit
    Clonality
    • 38
    • 12
    Polyclonal
    Conjugate
    • 32
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This CDC23 antibody is un-conjugated
    Application
    • 27
    • 16
    • 6
    • 5
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    17 amino acid peptide near the center of human APC8
    Top Product
    Discover our top product CDC23 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store the antibody (in aliquots) at -20 °C.
  • Target
    CDC23 (Cell Division Cycle 23 (CDC23))
    Alternative Name
    CDC23 / APC8 (CDC23 Products)
    Synonyms
    CDC23 antibody, anaphase-promoting complex subunit 8 antibody, zgc:56013 antibody, 6030435O18 antibody, D18Ertd243e antibody, ANAPC8 antibody, APC8 antibody, CUT23 antibody, cell division cycle 23 antibody, cell division cycle protein 23 homolog antibody, anaphase-promoting complex subunit 8 antibody, CDC23 (cell division cycle 23, yeast, homolog) antibody, cell division cycle 23 S homeolog antibody, CDC23 cell division cycle 23 antibody, CDC23 antibody, LOC100162672 antibody, LOC100380698 antibody, APC8 antibody, cdc23 antibody, cdc23.S antibody, Cdc23 antibody
    Background
    Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC8 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. In Drosophila, silencing of APC8 results in developmental delay and pupal lethality with elevated levels of apoptosis, high mitotic index, and delayed or blocked mitosis.Synonyms: ANAPC8, Anaphase-promoting complex subunit 8, Cell division cycle protein 23 homolog, Cyclosome subunit 8
    Gene ID
    8697
    NCBI Accession
    NP_004652
    UniProt
    Q9UJX2
    Pathways
    Protein targeting to Nucleus
You are here:
Support