TNFRSF1B antibody (C-Term)

Catalog No. ABIN784080

The Rabbit Polyclonal anti-TNFRSF1B antibody (ABIN784080) specifically detects TNFRSF1B in WB, IP and IHC (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TNFRSF1B antibody (C-Term) (ABIN784080)

Target: TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNFRSF1B antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TNFRSF1B Antibody

Binding Specificity: C-Term

Specificity: This antibody recognizes the C-term of TNFRSF1B / TNFR2.

Cross-Reactivity (Details): Species reactivity (expected):Human and Rat.
Species reactivity (tested):Mouse.

Purification: Immunoaffinity Chromatography

Immunogen: Synthetic peptide derived from C-terminal of Mouse TNF-R2

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 10 mM PBS, pH 7.4, Less that 0.1 % Sodium Azide, BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!

Target Details for TNFRSF1B

Target: TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))

Alternative Name: CD120b / TNFR2

Background: TNFR2 is a 75 kD transmembrane glycoprotein that also exists as a secreted protein. TNF receptors self assemble through a distinct functional extracellular domain termed PLAD in the absence of ligand. Efficient TNFA binding depends on receptor self assembly. TNFR2 has been shown to be responsible for stimulation of activated T lymphocytes by TNFalpha.Synonyms: TNF-R2, TNFBR, TNFRSF1B, Tumor necrosis factor receptor 2, Tumor necrosis factor receptor superfamily member 1B, Tumor necrosis factor receptor type II, p80 TNF-alpha receptor

Gene ID: 7133

NCBI Accession: NP_001057

Pathways: NF-kappaB Signaling, Apoptosis, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Ubiquitin Proteasome Pathway