Chromodomain Protein, Y-Like (CDYL) (N-Term) antibody

Details for Product No. ABIN785418
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Synonyms AI325931, CDYL1
(16), (15), (14), (3), (1), (1), (1)
Cow (Bovine), Human, Mouse (Murine), Rat (Rattus)
(48), (7), (6), (3), (3), (2), (1), (1), (1)
(29), (16), (3)
(3), (3), (3), (3), (3), (3)
Immunofluorescence (IF), Western Blotting (WB)
(45), (31), (5), (3), (2), (2), (2)
Pubmed 2 references available
Quantity 50 μg
Shipping to United States ( )
Availability Will be delivered in 2 to 3 Business Days
Immunogen Synthetic peptide directed towards the n terminal of human CDYL
Predicted Reactivity Dog : 100 %, Horse : 100 %, Human : 100 %, Bovine : 90 %, Chicken : 90 %, Guinea pig : 90 %, Mouse : 70 %, Rat : 70 %
Characteristics This is a rabbit polyclonal antibody against CDYL. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name CDYL (CDYL Antibody Abstract)
Background CDYL acts as repressor of transcription. CDYL has histone acetyltransferase activity, with a preference for histone H4.Chromodomain Y is a primate-specific Y-chromosomal gene family expressed exclusively in the testis and implicated in infertility. Although the Y-linked genes are testis-specific, this autosomal gene is ubiquitously expressed. The Y-linked genes arose by retrotransposition of an mRNA from this gene, followed by amplification of the retroposed gene. Proteins encoded by this gene superfamily possess a chromodomain, a motif implicated in chromatin binding and gene suppression, and a catalytic domain believed to be involved in histone acetylation. Multiple proteins are encoded by transcript variants of this gene.
Molecular Weight 60 kDa
Gene ID 9425
NCBI Accession NM_004824, NP_004815
UniProt Q9Y232
Research Area Chromatin and Nuclear Signaling
Application Notes Optimal working dilutions should be determined experimentally by the investigator.

Antigen size: 544 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Immunofluorescence (IF) image for anti-Chromodomain Protein, Y-Like (CDYL) (N-Term) antibody (ABIN785418) Sample Type: HeLa
Primary Antibody Dilution: 4 µg/mL
Secondary Antibody: ...
Immunofluorescence (IF) image for anti-Chromodomain Protein, Y-Like (CDYL) (N-Term) antibody (ABIN785418) Sample Type: MD MB231
Primary Antibody Dilution: 4 µg/mL
Secondary Antibo...
Product cited in: Li, Xia, Huang et al.: "A strategy to rapidly identify the functional targets of microRNAs by combining bioinformatics and mRNA cytoplasmic/nucleic ratios in culture cells." in: FEBS letters, Vol. 584, Issue 14, pp. 3198-202, 2010 (PubMed).

Background publications Nousiainen, Silljé, Sauer et al.: "Phosphoproteome analysis of the human mitotic spindle." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 14, pp. 5391-6, 2006 (PubMed).

Catalog No. ABIN785418
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