CDYL antibody (N-Term)

Catalog No. ABIN2783639

Cited in 1 publication. The Rabbit Polyclonal anti-CDYL antibody (ABIN2783639) specifically detects CDYL in WB and IF. The antibody is reactive with Human, Mouse, Rat, Dog, Cow, Horse, Guinea Pig and Rabbit samples.

Quick Overview for CDYL antibody (N-Term) (ABIN2783639)

Target: CDYL (Chromodomain Protein, Y-Like (CDYL))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDYL antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-CDYL Antibody

Binding Specificity: N-Term

Purpose: CDYL Antibody - N-terminal region

Sequence: YIHDFNRRHT EKQKESTLTR TNRTSPNNAR KQISRSTNSN FSKTSPKALV

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against CDYL. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the n terminal region of human CDYL

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49096-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-CDYL antibody (ABIN2783639)

Li, Xia, Huang, Chen, Su, Li, Wang, Ding, Shao: "A strategy to rapidly identify the functional targets of microRNAs by combining bioinformatics and mRNA cytoplasmic/nucleic ratios in culture cells." in: FEBS letters, Vol. 584, Issue 14, pp. 3198-202, (2010) (PubMed).

Target Details for CDYL

Target: CDYL (Chromodomain Protein, Y-Like (CDYL))

Alternative Name: CDYL

Background:

Background Information: CDYL acts as repressor of transcription. CDYL has histone acetyltransferase activity, with a preference for histone H4.Chromodomain Y is a primate-specific Y-chromosomal gene family expressed exclusively in the testis and implicated in infertility. Although the Y-linked genes are testis-specific, this autosomal gene is ubiquitously expressed. The Y-linked genes arose by retrotransposition of an mRNA from this gene, followed by amplification of the retroposed gene. Proteins encoded by this gene superfamily possess a chromodomain, a motif implicated in chromatin binding and gene suppression, and a catalytic domain believed to be involved in histone acetylation. Multiple proteins are encoded by transcript variants of this gene.

Gene Name: Chromodomain protein, Y-like

Alternative Symbols: CDYL1

Protein Name: Chromodomain Y-like protein

Molecular Weight: 60kDa

Gene ID: 9425

NCBI Accession: NP_004815

UniProt: Q9Y232