CDK19 antibody (AA 492-501)

Catalog No. ABIN793215

Product Details anti-CDK19 Antibody

Target: CDK19 (Cyclin-Dependent Kinase 19 (CDK19))

Binding Specificity: AA 492-501

Reactivity: Human, Rat, Cow, Rabbit, Horse, Monkey, Bat

Host: Goat

Clonality: Polyclonal

Conjugate: This CDK19 antibody is un-conjugated

Application: ELISA

Specificity: Human CDK19 / CDC2L6.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Rat, Bat, Bovine, Horse, Rabbit (100%) Gibbon, Hamster, Dog, Opossum, Platypus (90%) Mouse, Elephant, Panda, Turkey, Chicken, Lizard (80%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-QYHPSHQAHR from the C-terminus of human CDK19 / CDC2L6 (NP_055891.1). Percent identity by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Rat, Bat, Bovine, Horse, Rabbit (100%), Gibbon, Hamster, Dog, Opossum, Platypus (90%), Mouse, Elephant, Panda, Turkey, Chicken, Lizard (80%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: Peptide-ELISA (1:8000)

Usage: Peptide ELISA: antibody detection limit dilution 1:8000. Western blot: Preliminary experiments gave bands at approx 45kD and 20kD in Rat Eye lysates after 1 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calculated size of 56.6kD according to Rat NP_001101104.1. Both detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain the additional bands).

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for CDK19

Target: CDK19 (Cyclin-Dependent Kinase 19 (CDK19))

Alternative Name: CDK19 / CDK11 (CDK19 Products)

Synonyms: CDC2L6 antibody, CDK11 antibody, bA346C16.3 antibody, 2700084L06Rik antibody, AI845279 antibody, AW228747 antibody, Cdc2l6 antibody, mKIAA1028 antibody, Cdk11 antibody, cyclin dependent kinase 19 antibody, cyclin-dependent kinase 19 antibody, CDK19 antibody, Cdk19 antibody

Background: Name/Gene ID: CDK19
Subfamily: CDC2/CDK
Family: Protein Kinase

Synonyms: CDK19, BA346C16.3, CDC2L6, CDK11, CDC2-related protein kinase 6, Cyclin-dependent kinase 19, Cyclin-dependent kinase 11, Death-preventing kinase, KIAA1028

Gene ID: 23097

NCBI Accession: NP_055891

UniProt: Q9BWU1

Pathways: Regulation of Lipid Metabolism by PPARalpha