LOX antibody (AA 22-168)

Catalog No. ABIN2725060

The Mouse Monoclonal anti-LOX antibody is suitable to detect LOX in samples from Human. It has been validated for WB, IHC, FACS and IF.

Quick Overview for LOX antibody (AA 22-168) (ABIN2725060)

Target: LOX (Lysyl Oxidase (LOX))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LOX antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: 9G2

Product Details anti-LOX Antibody

Binding Specificity: AA 22-168

Characteristics: Homo sapiens lysyl oxidase (LOX), transcript variant 1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Human recombinant protein fragment corresponding to amino acids 22-168 of human LOX (NP_002308) produced in HEK293T cell.

Isotype: IgG1

Application Details

Application Notes: WB 1:500, IHC 1:150, IF 1:100, FLOW 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS ( pH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for LOX

Target: LOX (Lysyl Oxidase (LOX))

Alternative Name: LOX

Background: The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 46.8 kDa

Gene ID: 4015

NCBI Accession: NM_002317

HGNC: 4015

Pathways: SARS-CoV-2 Protein Interactome