CYB5R3 antibody

Catalog No. ABIN2718916

This Mouse Monoclonal antibody specifically detects CYB5R3 in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for CYB5R3 antibody (ABIN2718916)

Target: CYB5R3 (Cytochrome B5 Reductase 3 (CYB5R3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CYB5R3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: 1E8

Product Details anti-CYB5R3 Antibody

Characteristics: Homo sapiens cytochrome b5 reductase 3 (CYB5R3), transcript variant 1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human CYV5R3(NP_000389) produced in HEK293T cell.

Isotype: IgG1

Application Details

Application Notes: WB 1:500~2000, IHC 1:150, IF 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for CYB5R3

Target: CYB5R3 (Cytochrome B5 Reductase 3 (CYB5R3))

Alternative Name: CYB5R3

Background: This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias.

Molecular Weight: 34.1 kDa

Gene ID: 1727

NCBI Accession: NM_000398

HGNC: 1727

Pathways: SARS-CoV-2 Protein Interactome