KEAP1 antibody

Catalog No. ABIN2724100

The Mouse Monoclonal anti-KEAP1 antibody is suitable to detect KEAP1 in samples from Human. It has been validated for WB and FACS.

Quick Overview for KEAP1 antibody (ABIN2724100)

Target: KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KEAP1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: 1A1

Product Details anti-KEAP1 Antibody

Characteristics: Homo sapiens kelch-like ECH-associated protein 1 (KEAP1), transcript variant 1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human KEAP1 (NP_987096) produced in HEK293T cell.

Isotype: IgG1

Application Details

Application Notes: WB 1:2000, FLOW 1:100

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for KEAP1

Target: KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))

Alternative Name: KEAP1

Background: This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.

Molecular Weight: 69.5 kDa

Gene ID: 9817

NCBI Accession: NM_203500

HGNC: 9817

Pathways: Maintenance of Protein Location