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KEAP1 antibody (AA 380-624)

KEAP1 Reactivity: Human WB, ELISA, IHC, FACS Host: Mouse Monoclonal 7G4B10 unconjugated
Catalog No. ABIN1098141
  • Target See all KEAP1 Antibodies
    KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
    Binding Specificity
    • 21
    • 15
    • 15
    • 15
    • 10
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 380-624
    Reactivity
    • 88
    • 57
    • 29
    • 20
    • 18
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    Human
    Host
    • 91
    • 6
    • 1
    Mouse
    Clonality
    • 90
    • 8
    Monoclonal
    Conjugate
    • 43
    • 10
    • 8
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This KEAP1 antibody is un-conjugated
    Application
    • 85
    • 49
    • 32
    • 26
    • 26
    • 16
    • 10
    • 8
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human KEAP1 (AA: 380-624 ) expressed in E. coli.
    Clone
    7G4B10
    Isotype
    IgG1
    Top Product
    Discover our top product KEAP1 Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Muscarella, Barbano, DAngelo, Copetti, Coco, Balsamo, la Torre, Notarangelo, Troiano, Parisi, Icolaro, Catapano, Valori, Pellegrini, Merla, Carella, Fazio, Parrella: "Regulation of KEAP1 expression by promoter methylation in malignant gliomas and association with patient's outcome." in: Epigenetics, Vol. 6, Issue 3, pp. 317-25, (2011) (PubMed).

    Niture, Jaiswal: "INrf2 (Keap1) targets Bcl-2 degradation and controls cellular apoptosis." in: Cell death and differentiation, Vol. 18, Issue 3, pp. 439-51, (2011) (PubMed).

  • Target
    KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
    Alternative Name
    KEAP1 (KEAP1 Products)
    Synonyms
    INrf2 antibody, KLHL19 antibody, INRF2 antibody, mKIAA0132 antibody, Inrf2 antibody, fb36f11 antibody, keap1 antibody, wu:fb36f11 antibody, KEAP1 antibody, klhl19 antibody, zgc:171654 antibody, kelch like ECH associated protein 1 antibody, kelch-like ECH-associated protein 1 antibody, Kelch-like ECH-associated protein 1 antibody, kelch-like ECH-associated protein 1a antibody, kelch like ECH associated protein 1 L homeolog antibody, kelch-like ECH-associated protein 1b antibody, KEAP1 antibody, Keap1 antibody, keap1a antibody, keap1 antibody, keap1.L antibody, keap1b antibody
    Background

    Description: This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. , ,

    Aliases: INrf2, KLHL19

    Molecular Weight
    69.7 kDa
    Gene ID
    9817
    HGNC
    9817
    Pathways
    Maintenance of Protein Location
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