ARFGAP1 antibody

Catalog No. ABIN2716322

The Mouse Monoclonal anti-ARFGAP1 antibody (Clone 1F6) (ABIN2716322) specifically detects ARFGAP1 in WB, IHC, IF and FACS. The antibody is reactive with Human and Monkey samples.

Quick Overview for ARFGAP1 antibody (ABIN2716322)

Target: ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))

Reactivity: Human, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This ARFGAP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 1F6

Product Details anti-ARFGAP1 Antibody

Characteristics: Homo sapiens ADP-ribosylation factor GTPase activating protein 1 (ARFGAP1), transcript variant 2

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human ARFGAP1 (NP_783202) produced in HEK293T cell.

Isotype: IgG2b

Application Details

Application Notes: WB 1:1000~2000, IHC 1:150, IF 1:100, FLOW 1:100

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for ARFGAP1

Target: ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))

Alternative Name: ARFGAP1

Background: The protein encoded by this gene is a GTPase-activating protein (GAP) which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1 (ARF1). The encoded protein promotes hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 45.5 kDa

Gene ID: 55738

NCBI Accession: NM_175609

HGNC: 55738

Pathways: p53 Signaling, ER-Nucleus Signaling, Unfolded Protein Response