PDE1B antibody
Quick Overview for PDE1B antibody (ABIN2728481)
Target
See all PDE1B AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Characteristics
- Homo sapiens phosphodiesterase 1B, calmodulin-dependent (PDE1B), transcript variant 1
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Purification
- Purified from mouse ascites fluids by affinity chromatography
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Immunogen
- Full length human recombinant protein of human PDE1B(NP_000915) produced in HEK293T cell.
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Isotype
- IgG2b
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Application Notes
- WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100,
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Comment
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The concentration of the product may vary between diferrent lots.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5-1.0 mg/mL
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Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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- PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))
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Alternative Name
- PDE1B
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Background
- Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1B, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 [PubMed 1326532]).
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Molecular Weight
- 61.2 kDa
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Gene ID
- 5153
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NCBI Accession
- NM_000924
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HGNC
- 5153
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Pathways
- Neurotrophin Signaling Pathway, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
Target
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