MTHFR antibody

Catalog No. ABIN865423

This Mouse Monoclonal antibody specifically detects MTHFR in WB, ELISA and IHC. It exhibits reactivity toward Human and Rat.

Quick Overview for MTHFR antibody (ABIN865423)

Target: MTHFR (Methylenetetrahydrofolate Reductase (NAD(P)H) (MTHFR))

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This MTHFR antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 5D3

Product Details anti-MTHFR Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human MTHFR expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: WB: 1/500 - 1/2000, IHC:1/200-1/1000, ELISA: Propose dilution 1/10000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100g/100l

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for MTHFR

Target: MTHFR (Methylenetetrahydrofolate Reductase (NAD(P)H) (MTHFR))

Alternative Name: MTHFR

Background: The protein encoded by this gene catalyzes the conversion of 5,10- methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency. Synonyms: MTHFR

Molecular Weight: 75kDa

Gene ID: 4524

Pathways: Methionine Biosynthetic Process