Cyclin D3 antibody

Catalog No. ABIN865425

The Mouse Monoclonal anti-Cyclin D3 antibody (Clone 6H4) (ABIN865425) specifically detects Cyclin D3 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for Cyclin D3 antibody (ABIN865425)

Target: Cyclin D3 (CCND3)

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cyclin D3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 6H4

Product Details anti-Cyclin D3 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human CCND3 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: WB: 1/500 - 1/2000, ELISA: Propose dilution 1/10000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100g/100l

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for Cyclin D3

Target: Cyclin D3 (CCND3)

Alternative Name: CCND3

Background: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. Synonyms: CCND3

Molecular Weight: 32kDa

Gene ID: 896

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process