Cyclin D3 antibody (C-Term)
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- Target See all Cyclin D3 (CCND3) Antibodies
- Cyclin D3 (CCND3)
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Binding Specificity
- AA 252-281, C-Term
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Cyclin D3 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Predicted Reactivity
- B
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This CCND3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 252-281 amino acids from the C-terminal region of human CCND3.
- Clone
- RB43029
- Isotype
- Ig Fraction
- Top Product
- Discover our top product CCND3 Primary Antibody
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anti-Cyclin D3 (CCND3) (AA 1-292) antibody
CCND3 Reactivity: Human WB, ELISA, IHC, IP, IF Host: Rabbit Polyclonal unconjugated
anti-Cyclin D3 (CCND3) (AA 121-220) antibodyCCND3 Reactivity: Human, Rabbit WB, ELISA, IF (cc), IHC (p), IF (p), FACS, IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Cyclin D3 (CCND3) (pThr283) antibodyCCND3 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, ICC, IF Host: Rabbit Polyclonal unconjugated
anti-Cyclin D3 (CCND3) (AA 136-292) antibodyCCND3 Reactivity: Human, Rat WB, FACS Host: Rabbit Polyclonal unconjugated
anti-Cyclin D3 (CCND3) (AA 1-292) antibodyCCND3 Reactivity: Human WB, PLA Host: Rabbit Polyclonal unconjugated
anti-Cyclin D3 (CCND3) (AA 1-292) antibodyCCND3 Reactivity: Human WB, IHC (p), IF Host: Mouse Polyclonal unconjugated
anti-Cyclin D3 (CCND3) (C-Term) antibodyCCND3 Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Sheep, Guinea Pig WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Cyclin D3 (CCND3) (AA 1-292) antibodyCCND3 Reactivity: Human WB, ELISA, IHC (p), IHC (fro), ICC Host: Rabbit Polyclonal unconjugated
anti-Cyclin D3 (CCND3) (AA 33-66), (N-Term) antibodyCCND3 Reactivity: Rat WB Host: Rabbit Polyclonal RB43404 unconjugated
anti-Cyclin D3 (CCND3) (pSer264) antibodyCCND3 Reactivity: Human DB Host: Rabbit Polyclonal RB42160 unconjugated
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- Application Notes
- WB: 1:1000. WB: 1:1000. IHC-P: 1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Expiry Date
- 6 months
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- Target
- Cyclin D3 (CCND3)
- Alternative Name
- CCND3 (CCND3 Products)
- Synonyms
- zgc:103502 antibody, CCND3 antibody, 9230106B05Rik antibody, AA682053 antibody, AL024085 antibody, AW146355 antibody, C78795 antibody, cyclin D3 antibody, ccnd3 antibody, CCND3 antibody, Ccnd3 antibody
- Background
- Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D3/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.
- Molecular Weight
- 32520
- NCBI Accession
- NP_001129489, NP_001129597, NP_001129598, NP_001751
- UniProt
- P30281
- Pathways
- Cell Division Cycle, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process
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