The Mouse Monoclonal anti-SMAD5 antibody is suitable to detect SMAD5 in samples from Human and Rat. It has been validated for WB, ELISA, IHC, IF and FACS.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Target
SMAD5
(SMAD, Mothers Against DPP Homolog 5 (SMAD5))
Alternative Name
SMAD5
Background
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). SMAD5 is required for normal development of the cardiovascular system in vivo, lack of the SMAD5 gene results in apoptosis of cardiac myocytes. 3 Upregulation of SMAD5 has been reported to mediate apoptosis of gastric epithelial cells induced by Helicobacter pylori infection. Tissue specificity: Ubiquitous. Synonyms: Dwfc, JV5-1, MADH5, DKFZp781C1895, DKFZp781O1323, SMAD5