CEP152 antibody (AA 901-1000)

Catalog No. ABIN872433

Product Details anti-CEP152 Antibody

Target: CEP152 (Centrosomal Protein 152kDa (CEP152))

Binding Specificity: AA 901-1000

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEP152 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CEP152

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CEP152

Target: CEP152 (Centrosomal Protein 152kDa (CEP152))

Alternative Name: CEP152 (CEP152 Products)

Synonyms: AI851464 antibody, mKIAA0912 antibody, RGD1305348 antibody, MCPH4 antibody, MCPH9 antibody, SCKL5 antibody, centrosomal protein 152 antibody, CEP152 antibody, Cep152 antibody

Background:

Synonyms: CE152_HUMAN, Centrosomal protein 152 kDa, Centrosomal protein of 152 kDa, Cep152, FLJ21594, KIAA0912, MCPH4.

Background: Defects in CEP152 are the cause of microcephaly primary type 4 (MCPH4). A disease defined as a head circumference more than 3 standard deviations below the age-related mean. Brain weight is markedly reduced and the cerebral cortex is disproportionately small. Despite this marked reduction in size, the gyral pattern is relatively well preserved, with no major abnormality in cortical architecture. Affected individuals are mentally retarded. Primary microcephaly is further defined by the absence of other syndromic features or significant neurological deficits due to degenerative brain disorder.

Gene ID: 22995

Pathways: M Phase