H2AFZ antibody (N-Term)

Catalog No. ABIN926722

This Rabbit Polyclonal antibody specifically detects H2AFZ in WB. It exhibits reactivity toward Human.

Quick Overview for H2AFZ antibody (N-Term) (ABIN926722)

Target: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This H2AFZ antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-H2AFZ Antibody

Binding Specificity: N-Term

Purification: Purified

Immunogen: H2 AFZ antibody was raised in rabbit using the N terminal of H2 FZ as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

H2AFZ Blocking Peptide, (ABIN936283), is also available for use as a blocking control in assays to test for specificity of this H2AFZ antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for H2AFZ

Target: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Alternative Name: H2AFZ

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. Synonyms: Polyclonal H2AFZ antibody, Anti-H2AFZ antibody, H2A histone family, member Z antibody, H2A.z antibody, H2A/z antibody, H2AZ antibody, MGC117173 antibody.

Pathways: Telomere Maintenance