H2AFZ antibody (H2A Histone Family, Member Z) (C-Term)

Details for Product anti-H2AFZ Antibody No. ABIN4889649, Supplier: Log in to see
Antigen
  • H2A.Z-1
  • H2A.z
  • H2A/z
  • H2AZ
  • H2A.Z
  • H2a.z-1
  • H2AFV
  • H2Az
  • XH2AZ
  • h2a.zl1
  • h2a.zl2
  • H2A histone family member Z
  • H2A histone family, member Z
  • H2A histone family member Z L homeolog
  • histone H2A.Z
  • H2AFZ
  • H2afz
  • h2afz.L
Alternatives
anti-Human H2AFZ antibody for Immunocytochemistry
Epitope
C-Term
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16
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11
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2
2
2
2
1
1
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Reactivity
Human
136
66
59
9
6
6
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6
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1
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Host
Rabbit
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3
Clonality
Polyclonal
Conjugate
This H2AFZ antibody is un-conjugated
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3
3
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2
1
1
1
1
1
1
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1
Application
ChIP DNA-Sequencing (ChIPSeq), Chromatin Immunoprecipitation (ChIP), Dot Blot (DB), Western Blotting (WB)
125
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24
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10
6
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1
Options
Supplier
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Immunogen This Histone H2A.Z antibody was raised against a peptide derived from the C-terminus of human histone H2A.Z.
Purification None
Plasmids, Primers & others Plasmids, Primers & others H2AFZ products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name Histone H2A.Z (H2AFZ Antibody Abstract)
Background The nucleosome is the smallest subunit of chromatin and consists of 147 base pairs of DNA wrapped around an octamer of core histone proteins (two each of Histone H2A, Histone H2B, Histone H3 and Histone H4). Histone H2A.Z (H2AZ, H2AFZ) is a histone H2A variant, a protein similar to canonical H2A but with different molecular identity and unique functions. H2A.Z is highly conserved during evolution. It plays an important role in basic cellular mechanisms such as gene activation, chromosome segregation, heterochromatic silencing and progression through the cell cycle. H2A.Z is acetylated at multiple lysine residues in its amino terminus, which may serve to allow H2A.Z to function as an insulator of chromatin domains.
Molecular Weight 14 kDa
Gene ID 3015
Pathways Telomere Maintenance
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Storage -20 °C
Storage Comment Antibodies in solution can be stored at -20 °C for 2 years.
Expiry Date 6 months
Supplier Images
Chromatin Immunoprecipitation (ChIP) image for anti-H2A Histone Family, Member Z (H2AFZ) (C-Term) antibody (ABIN4889649) Histone H2A.Z antibody tested by ChIP analysis. Chromatin IP performed using the ChIP...
ChIP DNA-Sequencing (ChIPSeq) image for anti-H2A Histone Family, Member Z (H2AFZ) (C-Term) antibody (ABIN4889649) Histone H2A.Z antibody tested by ChIP-Seq. ChIP was performed using the ChIP-IT® High...
Dot Blot (DB) image for anti-H2A Histone Family, Member Z (H2AFZ) (C-Term) antibody (ABIN4889649) Histone H2A.Z antibody tested by dot blot analysis. Dot blot analysis was used to con...
Western Blotting (WB) image for anti-H2A Histone Family, Member Z (H2AFZ) (C-Term) antibody (ABIN4889649) Histone H2A.Z antibody tested by Western blot. Detection of H2A.Z by Western blot. Th...
Product cited in: Law, Cheung: "Expression of Non-acetylatable H2A.Z in Myoblast Cells Blocks Myoblast Differentiation through Disruption of MyoD Expression." in: The Journal of biological chemistry, Vol. 290, Issue 21, pp. 13234-49, 2015 (PubMed).

Gemma, Ramagopalan, Down, Beyan, Hawa, Holland, Hurd, Giovannoni, Leslie, Ebers, Rakyan: "Inactive or moderately active human promoters are enriched for inter-individual epialleles." in: Genome biology, Vol. 14, Issue 5, pp. R43, 2014 (PubMed).

Menet, Pescatore, Rosbash: "CLOCK:BMAL1 is a pioneer-like transcription factor." in: Genes & development, Vol. 28, Issue 1, pp. 8-13, 2014 (PubMed).

Boyarchuk, Filipescu, Vassias, Cantaloube, Almouzni: "The histone variant composition of centromeres is controlled by the pericentric heterochromatin state during the cell cycle." in: Journal of cell science, Vol. 127, Issue Pt 15, pp. 3347-59, 2014 (PubMed).

Lau, Cheung: "Elucidating combinatorial histone modifications and crosstalks by coupling histone-modifying enzyme with biotin ligase activity." in: Nucleic acids research, Vol. 41, Issue 3, pp. e49, 2013 (PubMed).

Vierstra, Wang, John, Sandstrom, Stamatoyannopoulos: "Coupling transcription factor occupancy to nucleosome architecture with DNase-FLASH." in: Nature methods, Vol. 11, Issue 1, pp. 66-72, 2013 (PubMed).

Yu, Feng, Ruan, Komers, Kiviat, Bomsztyk: "Microplate-based platform for combined chromatin and DNA methylation immunoprecipitation assays." in: BMC molecular biology, Vol. 12, pp. 49, 2011 (PubMed).

El Gazzar, Liu, Yoza, McCall: "Dynamic and selective nucleosome repositioning during endotoxin tolerance." in: The Journal of biological chemistry, Vol. 285, Issue 2, pp. 1259-71, 2010 (PubMed).

Conerly, Teves, Diolaiti, Ulrich, Eisenman, Henikoff: "Changes in H2A.Z occupancy and DNA methylation during B-cell lymphomagenesis." in: Genome research, Vol. 20, Issue 10, pp. 1383-90, 2010 (PubMed).

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