H2AFZ antibody (C-Term)

Catalog No. ABIN655184

The Rabbit Polyclonal anti-H2AFZ antibody is suitable to detect H2AFZ in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for H2AFZ antibody (C-Term) (ABIN655184)

Target: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This H2AFZ antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB20139

Product Details anti-H2AFZ Antibody

Binding Specificity: AA 59-86, C-Term

Predicted Reactivity: B, E, C, Zf, D, M, Rb, X, Rat, Sh

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This H2AFZ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-86 amino acids from the C-terminal region of human H2AFZ.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for H2AFZ

Target: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Alternative Name: H2AFZ

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq].

Molecular Weight: 13553

Gene ID: 3015

NCBI Accession: NP_002097

UniProt: P0C0S5

Pathways: Telomere Maintenance