TYK2 antibody (C-Term)

Catalog No. ABIN927289

This Rabbit Polyclonal antibody specifically detects TYK2 in WB. It exhibits reactivity toward Human.

Quick Overview for TYK2 antibody (C-Term) (ABIN927289)

Target: TYK2 (Tyrosine Kinase 2 (TYK2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TYK2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TYK2 Antibody

Binding Specificity: C-Term

Purification: Purified

Immunogen: TYK2 antibody was raised in rabbit using the C terminal of TYK2 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for TYK2

Target: TYK2 (Tyrosine Kinase 2 (TYK2))

Alternative Name: TYK2

Background: This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. Synonyms: Polyclonal TYK2 antibody, Anti-TYK2 antibody, tyrosine kinase 2 antibody, JTK1 antibody.

Pathways: JAK-STAT Signaling, Hepatitis C