PDX1 antibody (N-Term)

Catalog No. ABIN927350

The Rabbit Polyclonal anti-PDX1 antibody is suitable to detect PDX1 in samples from Human and Mouse. It has been validated for WB.

Quick Overview for PDX1 antibody (N-Term) (ABIN927350)

Target: PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDX1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PDX1 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Mouse (Murine)

Purification: Purified

Immunogen: PDX1 antibody was raised in rabbit using the N terminal of Pdx1 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

PDX1 Blocking Peptide, (ABIN5615297), is also available for use as a blocking control in assays to test for specificity of this PDX1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for PDX1

Target: PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

Alternative Name: PDX1

Background: Pdx1 activates insulin and somatostatin gene transcription. It is a key regulator of islet peptide hormone expression but also responsible for the development of the pancreas, most probably by determining maturation and differentiation of common pancreatic precursor cells in the developing gut. It binds the DNA sequence 5'-CC[CT]TAATGGG-3'. Synonyms: Polyclonal Pdx1 antibody, Anti-Pdx1 antibody, pancreatic and duodenal homeobox 1 antibody, IDX-1 antibody, IPF-1 antibody, Ipf1 antibody, Mody4 antibody, STF-1 antibody, pdx-1 antibody.

Pathways: Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location