UBE2K antibody (Middle Region)

Catalog No. ABIN929037

The Rabbit Polyclonal anti-UBE2K antibody (ABIN929037) specifically detects UBE2K in WB. The antibody is reactive with Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Cow, Chicken, Xenopus laevis and Pig samples.

Quick Overview for UBE2K antibody (Middle Region) (ABIN929037)

Target: UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Cow, Chicken, Xenopus laevis, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBE2K antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-UBE2K Antibody

Binding Specificity: Middle Region

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Frog, Chicken, Zebrafish (Brachydanio rerio), Pig (Porcine), Cow (Bovine), Dog (Canine)

Purification: Purified

Immunogen: UBE2 K antibody was raised in rabbit using the middle region of UBE2 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

UBE2K Blocking Peptide, (ABIN5616871), is also available for use as a blocking control in assays to test for specificity of this UBE2K antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for UBE2K

Target: UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

Alternative Name: UBE2K

Background: UBE2K belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Synonyms: Polyclonal UBE2K antibody, Anti-UBE2K antibody, ubiquitin-conjugating enzyme E2K, UBC1 homolog, yeast antibody, DKFZp564C1216 antibody, DKFZp686J24237 antibody, E2-25K antibody, HIP2 antibody, HYPG antibody, LIG antibody.