TNFRSF4 antibody (Middle Region)

Catalog No. ABIN929123

The Rabbit Polyclonal anti-TNFRSF4 antibody is suitable to detect TNFRSF4 in samples from Human. It has been validated for WB.

Quick Overview for TNFRSF4 antibody (Middle Region) (ABIN929123)

Target: TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNFRSF4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TNFRSF4 Antibody

Binding Specificity: Middle Region

Purification: Purified

Immunogen: TNFRSF4 antibody was raised in rabbit using the middle region of TNFRSF4 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

TNFRSF4 Blocking Peptide, (ABIN938748), is also available for use as a blocking control in assays to test for specificity of this TNFRSF4 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for TNFRSF4

Target: TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))

Alternative Name: TNFRSF4

Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. Synonyms: Polyclonal TNFRSF4 antibody, Anti-TNFRSF4 antibody, tumor necrosis factor receptor superfamily, member 4 antibody, ACT35 antibody, CD134 antibody, OX40 antibody, TXGP1L antibody.

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints