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CD3 epsilon antibody (Middle Region)

CD3E Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN929127
  • Target See all CD3 epsilon (CD3E) Antibodies
    CD3 epsilon (CD3E)
    Binding Specificity
    • 25
    • 20
    • 16
    • 16
    • 16
    • 15
    • 13
    • 9
    • 8
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 218
    • 162
    • 44
    • 42
    • 18
    • 8
    • 8
    • 8
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    Human
    Host
    • 143
    • 118
    • 33
    • 22
    • 20
    • 8
    • 1
    Rabbit
    Clonality
    • 218
    • 121
    • 6
    Polyclonal
    Conjugate
    • 127
    • 31
    • 27
    • 20
    • 15
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD3 epsilon antibody is un-conjugated
    Application
    • 235
    • 158
    • 86
    • 82
    • 71
    • 70
    • 27
    • 27
    • 25
    • 22
    • 14
    • 14
    • 13
    • 13
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Purified
    Immunogen
    CD3 E antibody was raised in rabbit using the middle region of CD3 as the immunogen
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    Discover our top product CD3E Primary Antibody
  • Application Notes
    WB: 0.125 µg/mL
    Optimal conditions should be determined by the investigator.
    Comment

    CD3E Blocking Peptide, catalog no. 33R-7793, is also available for use as a blocking control in assays to test for specificity of this CD3E antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Concentration
    Lot specific
    Buffer
    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • Target
    CD3 epsilon (CD3E)
    Alternative Name
    CD3E (CD3E Products)
    Synonyms
    cd3e antibody, CD3E antibody, t3e antibody, tcre antibody, AI504783 antibody, CD3 antibody, CD3epsilon antibody, T3e antibody, T3E antibody, TCRE antibody, CD3e molecule antibody, CD3 antigen, epsilon polypeptide antibody, cd3e antibody, CD3E antibody, Cd3e antibody
    Background
    The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. Synonyms: Polyclonal CD3E antibody, Anti-CD3E antibody, CD3e molecule, epsilon, CD3-TCR complex antibody, FLJ18683 antibody, T3E antibody, TCRE antibody.
    Pathways
    TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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