PARL antibody (AA 112-167)

Catalog No. ABIN932520

The Mouse Monoclonal anti-PARL antibody (Clone 8C4B2-1H12E10) (ABIN932520) specifically detects PARL in ELISA and WB. The antibody is reactive with Human samples.

Quick Overview for PARL antibody (AA 112-167) (ABIN932520)

Target: PARL (Presenilin Associated, Rhomboid-Like (PARL))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PARL antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Clone: 8C4B2-1H12E10

Product Details anti-PARL Antibody

Binding Specificity: AA 112-167

Immunogen: PARL antibody was raised in Mouse using a purified recombinant fragment of PARL(aa112-167) expressed in E. coli as the immunogen.

Isotype: IgG2b

Application Details

Application Notes: ELISA: 1:10,000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Store at -20 °C for long term storage.

Target Details for PARL

Target: PARL (Presenilin Associated, Rhomboid-Like (PARL))

Alternative Name: PARL

Background: PARL is a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. Synonyms: Monoclonal PARL antibody, Anti-PARL antibody, Presenilin Associated Rhomboid-Like antibody, PRO2207 antibody, PSARL antibody, PSARL1 antibody, PSENIP2 antibody, RHBDS1 antibody.

Pathways: Autophagy