EPH Receptor A2 antibody

Catalog No. ABIN932744

The Mouse Monoclonal anti-EPH Receptor A2 antibody is suitable to detect EPH Receptor A2 in samples from Human. It has been validated for WB, ELISA and IHC.

Quick Overview for EPH Receptor A2 antibody (ABIN932744)

Target: EPH Receptor A2 (EPHA2)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EPH Receptor A2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 1B3C7

Product Details anti-EPH Receptor A2 Antibody

Immunogen: EPHA2 antibody was raised in Mouse using a purified recombinant fragment of EPHA2 expressed in E. coli as the immunogen.

Isotype: IgM

Application Details

Application Notes: ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Store at -20 °C for long term storage.

Target Details for EPH Receptor A2

Target: EPH Receptor A2 (EPHA2)

Alternative Name: EPHA2

Background: The Eph family of receptors is the largest known subfamily of receptor tyrosine kinases (RTk). Eph RTks and their ligands, the ephrins, are frequently overexpressed in a variety of cancers and tumor cell lines. One Eph family member, EPHA2, is also overexpressed in a wide variety of cancers, including breast, small-cell lung and gastrointestinal cancers, melanomas, and neuroblastomas. The ephrin-Eph interactions are important in development, especially in cell-cell interactions involved in nervous system patterning and possibly in cancer. Synonyms: Monoclonal EPHA2 antibody, Anti-EPHA2 antibody, Ephrin receptor EPHA2 antibody, epoxide hydrolase 1 microsomal (xenobiotic) antibody.

Pathways: RTK Signaling