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CD36 (Thrombospondin Receptor) (CD36) antibody

Antigen

CD36 (Thrombospondin Receptor) (CD36)

Synonyms FAT, GP4, GP3B, GPIV, CHDS7, PASIV, SCARB3
Clonality Monoclonal (TR9)
Host
Alternatives

Mouse

Reactivity
Alternatives

Human

Application
Alternatives Flow Cytometry (FACS)
Catalog no. ABIN94082
Quantity 0.1 mg  (1 mg/ml)
Price 260.00 $   Plus shipping costs $35.00
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Availability Ships within 3 to 5 Business days

Additional Information

Alternative name CD36
Immunogen Platelets
Format Purified
Isotype IgG1  (Matching secondary antibodies)
Clone TR9
Description CD36 (fatty acid translocase, FAT) is an 88 kDa ditopic glycosylated protein that belongs tothe class B family of scavenger receptors. CD36 is expressed by most resting marginal zoneB cells but not by follicular and B1 B cells, and it is rapidly induced on Follicular B cells invitro upon TLR and CD40 stimulation. CD36 does not affect the development of B cells, butmodulates both primary and secondary antibody response. Similarly to glucose transporterGLUT4, CD36 is translocated from intracellular pools to the plasma membrane following cellstimulation by insulin. In mouse, CD36 is responsible for gustatory perception of long-chainfatty acids.
Specificity The antibody TR9 reacts with CD36 (GPIIIb), a 85 kDa integral membrane glycoproteinexpressed on platelets, macrophages, endothelial cells, early erythroid cells andmegakaryocytes. The antibody TR9 cross-blocks binding of FITC-labeled standard antibodyOKM5.Anti-CD36 antibodies inhibit adhesive functions (e.g. adherence of infected erythrocytes totarget cells).

Application Details

Concentration 1 mg/ml
Purity > 95% (by SDS-PAGE)
Purification Purified from ascites by precipitation methods and ion exchange chromatography.
Buffer 20 mM Tris/HCl with 15 mM sodium azide, approx. pH 7.4
Storage Store at 2-8 o C. Do not use after expiration date stamped on vial label. For long-term storage aliquot and store at -20 o C. Avoid freeze/thaw cycles.
Research Area Cancer, Atherosclerosis, Hematopoietic Progenitors, Hematopoietic Stem Cells, CD Antigens, Surface Receptors of Immune Cells
Restrictions For Research Use only