Kallikrein-Related Peptidase 3 (KLK3) antibody

Antigen: Kallikrein-Related Peptidase 3 (KLK3)

Synonyms: APS, PSA, hK3, KLK2A1, KLK3, KLKB1

Clonality: Monoclonal (A67-B-E3)

Host: Mouse

Reactivity: Human

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Radioimmunoassay (RIA)

Catalog no.: ABIN94459

Additional Information

Alternative name: Prostate-specific antigen (PSA)

Immunogen: 30 KDa protein fraction prepared from human seminal plasma

Format: Purified

Isotype: IgG1  (Matching secondary antibodies)

Clone: A67-B-E3

Description: Prostate-specific antigen (PSA) is a protein produced by normal prostate cells. Thisenzyme participates in the dissolution of the seminal fluid coagulum and plays an importantrole in fertility. The highest amounts of PSA are found in the seminal fluid, some PSAescapes the prostate and can be found in the serum. This serum component has been usedto track the response to therapy in men with prostate cancer.ISOBM TD-3 PSA Workshop code: 207

Specificity: The antibody A67-B/E3 reacts with prostate-specific antigen (PSA),a protein produced bynormal prostate cells. The highest amounts of PSA are found in the seminal fluid.

Application Details

Application Notes: Western Blotting - Positive material: seminal plasma

Concentration: 1 mg/ml

Purity: > 95% (by SDS-PAGE)

Purification: Purified from ascites by precipitation methods.

Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

Storage: Store at 2-8 o C. Do not use after expiration date stamped on vial label. For long-term storage aliquot and store at -20 o C. Avoid freeze/thaw cycles.

Research Area: Cell/Tissue Markers, Cancer

Restrictions: For Research Use only