Prostate Specific Antigen antibody (AA 1-100)

Catalog No. ABIN3022795

The Rabbit Polyclonal anti-Prostate Specific Antigen antibody (ABIN3022795) specifically detects Prostate Specific Antigen in IHC, WB, IF and IP. The antibody is reactive with Human samples.

Quick Overview for Prostate Specific Antigen antibody (AA 1-100) (ABIN3022795)

Target: Prostate Specific Antigen (PSA)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prostate Specific Antigen antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-Prostate Specific Antigen Antibody

Binding Specificity: AA 1-100

Sequence: MWVPVVFLTL SVTWIGAAPL ILSRIVGGWE CEKHSQPWQV LVASRGRAVC GGVLVHPQWV LTAAHCIRNK SVILLGRHSL FHPEDTGQVF QVSHSFPHPL

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human KLK3 (NP_001639.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200,IP,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Prostate Specific Antigen

Target: Prostate Specific Antigen (PSA)

Alternative Name: KLK3

Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.,KLK3,APS,KLK2A1,PSA,hK3,Cancer,Tumor immunology,Tumor-associated antigens,Tumor biomarkers,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Extracellular Matrix,Immunology & Inflammation,Neuroscience,Cell Type Marker,Cardiovascular,Angiogenesis,KLK3

Molecular Weight: 7 kDa/23 kDa/25 kDa/26 kDa/28 kDa

Gene ID: 354

UniProt: P07288

Pathways: Complement System