You are viewing an incomplete version of our website. Please click to reload the website as full version.

Actin-Binding rho Activating Protein (ABRA) (AA 282-312), (C-Term) antibody

Details for Product No. ABIN950219, Supplier: Log in to see
Antigen
  • STARS
  • C130068O12Rik
  • Ms1
  • Stars
Epitope
C-Term, AA 282-312
18
15
2
1
1
Reactivity
Human
22
3
Host
Rabbit
23
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
22
14
14
2
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Available images

Immunogen KLH conjugated synthetic peptide between 282-312 amino acids from the C-terminal region of human ABRA
Isotype Ig
Specificity This antibody reacts to ABRA / STARS.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name ABRA / STARS (ABRA Antibody Abstract)
Background ABRA acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling (By similarity).Synonyms: Actin-binding Rho-activating protein, Striated muscle activator of Rho-dependent signaling
Gene ID 137735
NCBI Accession NP_631905
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Actin-Binding rho Activating Protein (ABRA) (AA 282-312), (C-Term) antibody (ABIN950219) ABRA Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin e...
Western Blotting (WB) image for anti-Actin-Binding rho Activating Protein (ABRA) (AA 282-312), (C-Term) antibody (ABIN950219) ABRA Antibody (C-term) western blot analysis in human normal Uterus cell line lysates...
Background publications Lamon, Wallace, Léger et al.: "Regulation of STARS and its downstream targets suggest a novel pathway involved in human skeletal muscle hypertrophy and atrophy." in: The Journal of physiology, Vol. 587, Issue Pt 8, pp. 1795-803, 2009 (PubMed).

Kuwahara, Teg Pipes, McAnally et al.: "Modulation of adverse cardiac remodeling by STARS, a mediator of MEF2 signaling and SRF activity." in: The Journal of clinical investigation, Vol. 117, Issue 5, pp. 1324-34, 2007 (PubMed).

Kuwahara, Barrientos, Pipes et al.: "Muscle-specific signaling mechanism that links actin dynamics to serum response factor." in: Molecular and cellular biology, Vol. 25, Issue 8, pp. 3173-81, 2005 (PubMed).

Arai, Spencer, Olson: "STARS, a striated muscle activator of Rho signaling and serum response factor-dependent transcription." in: The Journal of biological chemistry, Vol. 277, Issue 27, pp. 24453-9, 2002 (PubMed).

Simpson, Wellenreuther, Poustka et al.: "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing." in: EMBO reports, Vol. 1, Issue 3, pp. 287-92, 2001 (PubMed).