ADAMTS10 antibody (N-Term)

Catalog No. ABIN950271

Product Details anti-ADAMTS10 Antibody

Target: ADAMTS10 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 10 (ADAMTS10))

Binding Specificity: AA 217-248, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAMTS10 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to ADAMTS10.

Cross-Reactivity (Details): Species reactivity (tested):Human and Mouse.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 217-248 amino acids from the N-terminal region of human ADAMTS10

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ADAMTS10

Target: ADAMTS10 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 10 (ADAMTS10))

Alternative Name: ADAMTS10 (ADAMTS10 Products)

Synonyms: 9430006O18 antibody, AW045948 antibody, Adam-ts10 antibody, Adamts-10 antibody, Znmp antibody, ADAM-TS10 antibody, ADAMTS-10 antibody, WMS antibody, WMS1 antibody, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10 antibody, ADAM metallopeptidase with thrombospondin type 1 motif 10 antibody, ADAM metallopeptidase with thrombospondin type 1 motif, 10 antibody, Adamts10 antibody, ADAMTS10 antibody

Background: This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome.Synonyms: A disintegrin and metalloproteinase with thrombospondin motifs 10

Gene ID: 81794

NCBI Accession: NP_112219