Carbonyl Reductase 3 (CBR3) (C-Term), (AA 194-224) antibody

Details for Product No. ABIN951030
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Antigen
Synonyms MGC81473, CBR3, SDR21C2, hCBR3, 1110001J05Rik, C81353
Epitope
C-Term, AA 194-224
(17), (4), (3), (2), (2), (1), (1), (1)
Reactivity
Human
(49), (16), (13), (3), (2), (2), (1)
Host
Rabbit
(26), (20), (6)
Clonality
Polyclonal
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
(41), (30), (14), (5), (4), (3), (3), (2), (2), (2)
Pubmed 3 references available
Quantity 0.4 mL
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Request Want additional data for this product?

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Catalog No. ABIN951030
357.50 $
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Immunogen KLH conjugated synthetic peptide between 194-224 amino acids from the C-terminal region of human CBR3
Isotype Ig
Specificity This antibody reacts to CBR3.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Saturated Ammonium Sulfate (SAS) precipitation
Alternative Name Carbonyl Reductase 3
Background Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1.Synonyms: CBR3, NADPH-dependent carbonyl reductase 3
Molecular Weight 30850 Da
Gene ID 874
NCBI Accession NP_001227
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Zhang, Blanco: "Identification of the promoter of human carbonyl reductase 3 (CBR3) and impact of common promoter polymorphisms on hepatic CBR3 mRNA expression." in: Pharmaceutical research, Vol. 26, Issue 9, pp. 2209-15, 2009 (PubMed).

Hosgood, Menashe, He et al.: "PTEN identified as important risk factor of chronic obstructive pulmonary disease." in: Respiratory medicine, Vol. 103, Issue 12, pp. 1866-70, 2009 (PubMed).

Guey, García-Closas, Murta-Nascimento et al.: "Genetic susceptibility to distinct bladder cancer subphenotypes." in: European urology, Vol. 57, Issue 2, pp. 283-92, 2010 (PubMed).

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