ACTR1A antibody (ARP1 Actin-Related Protein 1 Homolog A, Centractin alpha (Yeast)) (AA 97-126)

Details for Product anti-ACTR1A Antibody No. ABIN951473, Supplier: Log in to see
Antigen
  • ACTR1A
  • arp1
  • centractin
  • ctrn1
  • ARP1
  • CTRN1
  • Arp1
  • alpha-Arp1
  • ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
  • alpha-centractin
  • ARP1 actin-related protein 1 homolog A, centractin alpha
  • ARP1 actin-related protein 1A, centractin alpha
  • ACTR1A
  • PTRG_02540
  • PAAG_06972
  • MCYG_01044
  • VDBG_00685
  • MGYG_00946
  • DICPUDRAFT_88548
  • PGTG_04034
  • Tsp_06409
  • actr1a
  • Actr1a
Alternatives
anti-Mouse (Murine) ACTR1A antibody for ELISA
Epitope
AA 97-126, Middle Region
14
11
10
7
4
4
2
2
2
1
1
1
1
Reactivity
Human, Mouse (Murine)
61
56
35
5
3
3
3
3
2
2
2
2
2
1
1
Host
Rabbit
61
11
5
Clonality
Polyclonal
Conjugate
This ACTR1A antibody is un-conjugated
4
4
4
3
3
3
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
53
40
13
8
4
1
1
Options
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Immunogen KLH conjugated synthetic peptide between 97-126 amino acids from the Central region of human ACTR1A
Isotype Ig
Specificity This antibody reacts to Centractin alpha.
Cross-Reactivity (Details) Species reactivity (tested):Mouse.
Purification Affinity chromatography on Protein A
Alternative Name Centractin alpha (ACTR1A Antibody Abstract)
Background This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60 % identical at the amino acid level to conventional actin.Synonyms: ACTR1A, ARP1, Actin-RPV, CTRN1, Centrosome-associated actin homolog
Gene ID 10121
NCBI Accession NP_005727
Pathways M Phase
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-ACTR1A antibody (ARP1 Actin-Related Protein 1 Homolog A, Centractin alpha (Yeast)) (AA 97-126) (ABIN951473) ACTR1A Antibody (Center) western blot analysis in mouse cerebellum tissue lysates (35...
Background publications Sugarbaker, Richards, Gordon, Dong, De Rienzo, Maulik, Glickman, Chirieac, Hartman, Taillon, Du, Bouffard, Kingsmore, Miller, Farmer, Jensen, Gullans, Bueno: "Transcriptome sequencing of malignant pleural mesothelioma tumors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 9, pp. 3521-6, 2008 (PubMed).

Petretti, Savoian, Montembault, Glover, Prigent, Giet: "The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation." in: EMBO reports, Vol. 7, Issue 4, pp. 418-24, 2006 (PubMed).